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*Correspondence: Zuzana Pilsova, [email protected]

2022 Feb 1;45(1):1120

Sources: Mayo Clinic: Semaglutide (Subcutaneous Route) Wegovy: Starting Wegovy Pill Diabetes Care: Gradual Titration of Semaglutide Results in Better Tolerability Ozempic: Dosing Information Wharton S, Freitas P, Hjelmesaeth J, et al

When IV therapy is used appropriately, the benefits are substantial: Rapid symptom relief as dizziness, weakness, confusion, and heart palpitations can improve within minutes to hours Organ protection as restoring blood volume and electrolyte balance prevents cascading damage to kidneys, heart, and brain Irregular heartbeat prevention from correcting the potassium and magnesium shortages that directly cause dangerous heart rhythms Shortened recovery time from acute illnesses when fluid and electrolyte gaps are corrected efficiently IV electrolyte therapy is very effective, but it carries real risks if the type, dose, or rate are wrong or if monitoring is poor: Fluid overload is a serious risk, defined as a body weight increase of 5 to 10% or a positive fluid balance of the same amount

64 Semi-synthesis of the (+)-decursin derivatives were synthesised by the esterification of decursinol by 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC)-mediated coupling